• Patients with AAG often respond to intravenous immunoglobuli

  2023-07-29

  

  Patients with AAG often respond to intravenous immunoglobulin or plasma exchange. If these therapies are inadequate, ongoing immune suppression with steroids, azathioprine, mycophenylate or rituximab have been shown to be effective in case reports. Our patient seemed initially resistant to steroid t

• Finally Urban Ciecko et al asked whether this

  2023-07-29

  

  Finally, Urban-Ciecko et al. (2018) asked whether this enhancement is specific to the pyramidal to SST neuron synapses or more generally observed in other synapses of the cortical microcircuit. Synapses between pyramidal cells showed no sign of potentiation after either bath application of the choli

• However for a molecular target to be useful

  2023-07-29

  

  However, for a molecular target to be useful in AD, it must rescue behavioral as well as biochemical insults. In humans, AD memory impairments typically declare themselves initially as disruption of episodic memory and consolidation of new memories, eventually progressing to global cognitive decline

• U 18666A Several tertiary prevention studies are currently u

  2023-07-29

  

  Several tertiary prevention studies are currently underway examining the use of dutasteride for prostate cancer treatment: (1) during expectant management of prostate cancer, (2) after radical prostatectomy in men at high risk for relapse, and (3) in men with metastatic disease. The Reduction by Dut

• Aurora A overexpression is also

  2023-07-29

  

  Aurora-A overexpression is also related to the activation of NF-κB, a potent anti-apoptotic effector that may play a role in preventing apoptosis in cancer HG-9-91-01 [18]. These data show that we are still at the beginning of unraveling the complex mechanism by which these gene products and prote

• To maintain ATP levels postmortem muscle mobilizes its

  2023-07-29

  

  To maintain ATP levels, postmortem muscle mobilizes its glycogen reserves to yield cox 2 inhibitors 6-phsphate that proceeds through glycolysis. Glycogen degradation was affected by the interaction between treatment and time (Pinitiation of the experiment. We expected that if myosin ATPase is limi

• Along with the improvement of the cadmium transport from roo

  2023-07-29

  

  Along with the improvement of the cadmium transport from roots to aerial tissues, as is required for phytoremediation, over-expression of PtoHMA5 also led to the excessive accumulation of cadmium in leaves that was harmful to plant growth and physiological performance. Thus, detoxification of the he

• br Introduction In addition to ATP production an

  2023-07-29

  

  Introduction In addition to ATP production, an important role of mitochondria in the pancreatic beta cell is anaplerosis, which is the net synthesis of citric SNOG cycle intermediates that are exported to the cytosol where they are converted to numerous other metabolites that stimulate and/or sup

• br Introduction Hepatocellular carcinoma HCC is an aggressiv

  2023-07-29

  

  Introduction Hepatocellular carcinoma (HCC) is an aggressive and malignant cancer detected in clinical practice, as it is the third key reason of tumor-related deaths worldwide, with > 800, 000 mortalities every year (Torre et al., 2015). Current treatments for HCC are surgical therapy, liver tra

• It is reported that calpain plays a

  2023-07-29

  

  It is reported that calpain-2 plays a critical role in BDNF-induced signaling and memory formation, and knockdown of calpain-2, but not calpain-1, completely suppresses BDNF-induced pathway activation and protein translation (Briz et al., 2013). BDNF prevents neuronal apoptosis or death (Ferrer et a

• br Results Four HT esters butyrate caprylate

  2023-07-29

  

  Results Four HT esters (butyrate, caprylate, laurate and stearate esters) were chosen as representative compounds of increasing lipophilicity (Fig. 1). We will refer to them as C4HT, C8HT, C12HT and C18HT, respectively. They have been synthesized, purified and characterized according to our previ

• The evaluation of serum electrolytes e g

  2023-07-29

  

  The evaluation of serum electrolytes (e.g.: sodium, potassium, urea, creatinine, and uric acid), liver transaminases, blood counts (e.g. identification of thrombocytopenia, and bilirubin), 24-h urine (in order to monitor proteinuria), and heart rate and lung function of the mother should be performe

• br Materials and methods br Results br

  2023-07-29

  

  Materials and methods Results Discussion Our results revealed that LPS injection in rats impaired fear memory in the PA task. This results are in agreement with the most of previous studies reported that following acute [23,24,39,[45], [46], [47]] or chronic systemic Chlorprothixene [30] f

• Perforation of the surface membrane however

  2023-07-29

  

  Perforation of the surface membrane, however, is not the only mechanism of calcium dysregulation by Aβ at the presynaptic terminals. When in excess, both monomers and oligomers modulate biophysical properties of voltage-activated calcium AZD4547 as well as calcium release from the endoplasmic retic

• br Conclusion These studies broadly demonstrate that dopamin

  2023-07-29

  

  Conclusion These studies broadly demonstrate that dopamine and endocannabinoid signaling in the NAc can have diverse effects on AMPAR-mediated synaptic function depending on previous psychostimulant experience. Here, we examined mechanisms underlying the depotentiation of AMPAR-mediated synaptic

15698 records 277/1047 page Previous Next First page 上5页 276277278279280 下5页 Last page