• br Discussion A familial platelet disorder with a propensity

  2019-04-25

  

  Discussion A familial platelet disorder with a propensity to myeloid malignancy (FPD/MM) was first reported in 1978 and since then approximately 30 pedigrees with RUNX1 germline mutations have been reported in the literature [9,11]. The RUNX1 gene is composed of 10 exons (1–6, 7A, 7B, 7C and 8).

• Introduction The hippocampus is a critical brain

  2019-04-25

  

  Introduction The hippocampus is a critical brain region for episodic memory formation in rodents and humans [1]. Hippocampal neurons, especially CA1 neurons, are highly vulnerable to ischemic injury [2], and failure of hippocampal function causes memory impairment and reduced cognitive ability [3,4

• Introduction Radiofrequency catheter ablation RFCA has

  2019-04-25

  

  Introduction Radiofrequency catheter ablation (RFCA) has been established as an effective and safe non-pharmacological therapy for arrhythmias [1]. Idiopathic left ventricular outflow tract ventricular arrhythmias (LVOT-VAs) arising from the LVOT are rare compared with VAs arising from the right ve

• As Table shows all guidelines recommend OACs for patients wi

  2019-04-25

  

  As Table 2 shows, all guidelines recommend OACs for patients with a CHADS2 score of ≥2, whereas recommendations for low-risk patients with a CHADS2 score of 0/1 differ slightly across guidelines. Evidence indicating that novel OACs decrease the risk of ICH by half as compared with warfarin has affec

• The incidence of AF in Japan was also reported

  2019-04-25

  

  The incidence of AF in Japan was also reported from an early cohort of the Hisayama Study [32] in the period between 1961 and 1984. Similar to the reports from Western countries, the incidence of AF increased with age in both men and women (Fig. 7) [32]. In a recent report of an observational cohort

• The majority of breast malignancies are hormone responsive a

  2019-04-25

  

  The majority of breast malignancies are hormone responsive, and adjuvant endocrine therapy is used routinely to prevent breast cancer recurrence and death [6,7]. Tamoxifen was the past treatment of choice for endocrine-responsive postmenopausal breast cancer and was found to preserve BMD in postmeno

• br Discussion The cardiac manifestations of organophosphorus

  2019-04-25

  

  Discussion The cardiac manifestations of organophosphorus poisoning are well known, involving various electrocardiographic abnormalities that may range from sinus tachycardia to ST elevation. Such most common abnormalities are sinus bradycardia, prolonged QT interval, and ST elevation [2–4]. Most

• This Ca overload activates the forward mode

  2019-04-25

  

  This Ca2+ overload activates the forward mode of the Na+/Ca+ exchanger (NCX), increases the transient inward current (Iti), and induces ventricular arrhythmias due to delayed after depolarizations (DADs). Subtypes of CPVT Several subtypes of CPVT have been reported (Table 1). The most common typ

• Introduction Neuroblastoma NB which arises from embryonal

  2019-04-24

  

  Introduction Neuroblastoma (NB), which arises from embryonal neural crest cells, is the most common extra-cranial solid tumor of childhood and accounts for more than 15% of all child cancer death [1,2]. Patients with NB frequently manifest disseminated disease at first visit and prognosis of these

• br Material and methods br Results

  2019-04-24

  

  Material and methods Results Discussion Previously, various small studies reported that CRT is an effective therapy in patients with NAHF [7,10–15]. These studies demonstrated favorable outcomes in patients treated with CRT, including the ability to wean patients from intravenous inotropes

• Detailed data were available in Kilifi not only on

  2019-04-24

  

  Detailed data were available in Kilifi not only on carriage of vaccine types of pneumococci, but also on receipt of vaccine by the individuals in the study, and the overall vaccine coverage in the tak1 inhibitor was also known. The data suggest that vaccine coverage of around two-thirds of children

• La cr tica realizada al ccpor las

  2019-04-24

  

  La crítica realizada al ccpor las diferentes comisiones develó la verticalidad en la toma de decisiones políticas, las cuales se agudizaban cuando se realizaban acciones militares, lo que ocasionó constantes fricciones y sanciones interleukin 1 receptor antagonist algunos miembros de la Comisión Mil

• alk inhibitor Obesity is not the only concern documented

  2019-04-23

  

  Obesity is not the only concern documented for BPA. Epidemiological studies have identified neurocognitive effects of BPA and newly incident coronary artery disease, and laboratory studies strongly suggest BPA is an ovarian toxicant. The rapidly rising evidence of adverse effects has prompted manufa

• br Discussion A previous report demonstrated an adenosine se

  2019-04-23

  

  Discussion A previous report demonstrated an adenosine-sensitive reentrant AT not involving an AV nodal pathway in the vicinity of the apex of Koch\'s triangle, which could be ablated at the earliest atrial activation site in the right supero-septal region [3]. Otomo et al. reported a “left-varia

• br Conclusion br Conflict of

  2019-04-23

  

  Conclusion Conflict of interest Introduction Loss-of-function mutations in the cardiac sodium (Na+) channel gene have been implicated in Brugada syndrome, progressive cardiac conduction defect (PCCD), sick sinus syndrome, and idiopathic ventricular fibrillation (IVF) [1]. In the present stu

16102 records 1070/1074 page Previous Next First page 上5页 10661067106810691070 下5页 Last page