• Because of high suspicion of malignancy we chose

  2019-04-26

  

  Because of high suspicion of malignancy, we chose endoscopic ultrasound (EUS) instead of MRI of the pancreas to detect the organic lesion that caused the distal CBD stricture because initial abdominal CT did not show any suspicious lesion in the pancreas. In addition, tissue sample could be obtained

• beta amyloid br Discussion The rate of ERP

  2019-04-26

  

  Discussion The rate of ERP in young, healthy men in northeastern Thailand was 10.3%. This is higher than the rate reported in the US (3.3–6.1%) [12]. In the US report, the mean age of the study population was 45 years, which was older than the age of subjects in our study. Another report from the

• Cryotherapy related soft tissue injury usually occurs within

  2019-04-25

  

  Cryotherapy related soft tissue injury usually occurs within a few weeks postoperatively. Skin necrosis is a significant complication if freezing of the superficial surface occurs. Constant irrigation of the adjacent tissues with warm saline reduces the chance of skin necrosis. Our rate of infection

• Concern about the effects on health of chemical exposure to

  2019-04-25

  

  Concern about the effects on health of chemical exposure to e-waste and e-waste recycling is increasing despite the paucity of solid research. Reported adverse effects include: fetal loss, prematurity, low birthweight, and congenital malformations; abnormal thyroid function and thyroid development;

• We agree that this method is an appropriate

  2019-04-25

  

  We agree that this method is an appropriate way to assess whether Buruli ulcer is over-represented in children, but this issue was not central to our study. We also felt that the introduction of external data, the quality of which we cannot assess and which might not be relevant to areas where Burul

• Express o territorial desta expans o no in cio

  2019-04-25

  

  Expressão territorial desta expansão, no início dos anos 1990 as concessões mineiras ocupavam 2.3 milhões de hectares, enquanto na atualidade, beiram 25 milhões. A atividade deixou de se concentrar nas alturas andinas expandindo‐se para os vales, palbociclib costa e inclusive a Amazônia. Há departam

• The deletion of q seen in our

  2019-04-25

  

  The deletion of 14q seen in our patient included the IGH locus at 14q32.33. This is noteworthy, because loss of 14q has been reported as a recurrent aberration acquired during the natural history of CLL. The acquisition of a del(14) may thus be indicative of CLL in transformation. In a study of a la

• br Discussion A familial platelet disorder with a propensity

  2019-04-25

  

  Discussion A familial platelet disorder with a propensity to myeloid malignancy (FPD/MM) was first reported in 1978 and since then approximately 30 pedigrees with RUNX1 germline mutations have been reported in the literature [9,11]. The RUNX1 gene is composed of 10 exons (1–6, 7A, 7B, 7C and 8).

• Introduction The hippocampus is a critical brain

  2019-04-25

  

  Introduction The hippocampus is a critical brain region for episodic memory formation in rodents and humans [1]. Hippocampal neurons, especially CA1 neurons, are highly vulnerable to ischemic injury [2], and failure of hippocampal function causes memory impairment and reduced cognitive ability [3,4

• Introduction Radiofrequency catheter ablation RFCA has

  2019-04-25

  

  Introduction Radiofrequency catheter ablation (RFCA) has been established as an effective and safe non-pharmacological therapy for arrhythmias [1]. Idiopathic left ventricular outflow tract ventricular arrhythmias (LVOT-VAs) arising from the LVOT are rare compared with VAs arising from the right ve

• As Table shows all guidelines recommend OACs for patients wi

  2019-04-25

  

  As Table 2 shows, all guidelines recommend OACs for patients with a CHADS2 score of ≥2, whereas recommendations for low-risk patients with a CHADS2 score of 0/1 differ slightly across guidelines. Evidence indicating that novel OACs decrease the risk of ICH by half as compared with warfarin has affec

• The incidence of AF in Japan was also reported

  2019-04-25

  

  The incidence of AF in Japan was also reported from an early cohort of the Hisayama Study [32] in the period between 1961 and 1984. Similar to the reports from Western countries, the incidence of AF increased with age in both men and women (Fig. 7) [32]. In a recent report of an observational cohort

• The majority of breast malignancies are hormone responsive a

  2019-04-25

  

  The majority of breast malignancies are hormone responsive, and adjuvant endocrine therapy is used routinely to prevent breast cancer recurrence and death [6,7]. Tamoxifen was the past treatment of choice for endocrine-responsive postmenopausal breast cancer and was found to preserve BMD in postmeno

• br Discussion The cardiac manifestations of organophosphorus

  2019-04-25

  

  Discussion The cardiac manifestations of organophosphorus poisoning are well known, involving various electrocardiographic abnormalities that may range from sinus tachycardia to ST elevation. Such most common abnormalities are sinus bradycardia, prolonged QT interval, and ST elevation [2–4]. Most

• This Ca overload activates the forward mode

  2019-04-25

  

  This Ca2+ overload activates the forward mode of the Na+/Ca+ exchanger (NCX), increases the transient inward current (Iti), and induces ventricular arrhythmias due to delayed after depolarizations (DADs). Subtypes of CPVT Several subtypes of CPVT have been reported (Table 1). The most common typ

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