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HCV does not kill the
2019-05-23
HCV does not kill the VE-822 it infects, but triggers an immune-mediated inflammatory response (hepatitis) that either rapidly clears the infection or slowly destroys the liver, causing the development of HCC and cirrhosis. The outcome is largely determined by the efficiency of the antiviral immune
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br Erythropoietin and the HSC niche Many
2019-05-23
Erythropoietin and the HSC niche Many molecules produced both locally and systemically, including erythropoietin (Epo) and adrenergic catecholamines, also appear to affect HSC niche and metastatic lesions in the bone marrow. EPO is a hematopoietic hormone produced predominantly in the kidneys in
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El libro de William Crawford publicado
2019-05-23
El libro de William Crawford publicado en 1944, traducido en 1966, y las obras de Leopoldo Zea de 1949 y de 1965, aunque de muy distinto carácter y alcance, suscitaron primero un artículo de Oscar Kubitz en 1960, después un ensayo de Salomon Lipp en 1975, y, finalmente, otro artículo de frank Spindl
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Computed tomography images of the chest revealed ground glas
2019-05-23
Computed tomography images of the chest revealed ground-glass opacities and honeycombing, suggestive of pneumonitis. She later required intubation for respiratory failure. To evaluate the troponin elevation, the patient had a transthoracic echocardiogram (Fig. 1A) that demonstrated echodense materia
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A review by Keung and colleagues summarized cases of hematol
2019-05-23
A 2002 review by Keung and colleagues summarized cases of hematologic malignancy in patients with KS reported between 1961 and 2002 [3]. They described 12 cases of AML in KS in the literature during that time period. Based on the review of the current literature, we found approximately 10 additional
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A previous study from our group demonstrated that
2019-05-23
A previous study from our group demonstrated that the truncated form of OPG (1-194) has greater activity than the complete form, given that proteoglycans present in the bone tumor microenvironment may bind to full length OPG, thereby limiting its bioavailability and bioactivity [31]. Therefore the t
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Importa notar al mismo tiempo cierta impaciencia con la
2019-05-22
Importa notar, al mismo tiempo, cierta impaciencia con la indeterminación del saber celebrada hasta no hace mucho. En la ruta hacia el neoliberalismo, ese tránsito del Estado al mercado —como suele llamársele en América Latina—, la duda epistémica, el pensamiento débil, los juegos de lenguaje y la
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The GCT usually involves a cladding that consisted of
2019-05-22
The GCT usually involves a cladding that consisted of reactive bone and fibrosis, with a distinct boundary surrounded by soft tissue. Nevertheless, the active cladding is very thin among patients with severe invasiveness, including tumors that extend directly in into the muscle and fat, or other sig
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br Las paradojas de un escritor norteamericano S
2019-05-22
Las paradojas de un escritor norteamericano Séptima novela de Hergesheimer, Tampico está considerada entre las menos artísticas que escribió. Tal vez el choque con la descarnada realidad del enclave petrolero vasopressin receptor antagonist puso en cuestión, hasta cierto punto, su vocación este
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In September a high level meeting of
2019-05-22
In September 2011, a high-level meeting of the UN called for a concerted global response to the growing challenge of non-communicable diseases (NCDs). Subsequently, in 2013, the World Health Assembly adopted a WHO-generated action plan and set a target of 25 × 25: a 25% reduction in premature mortal
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The ETV ABL fusion has been
2019-05-22
The ETV6-ABL1 fusion has been reported as a poor prognostic factor when found in acute leukemia (AML and ALL) and MDS. The prognostic significance of an ETV6/ABL1 chronic myeloproliferative neoplasm is less clear due to the paucity of cases and the lack of controlled clinical trials [5]. There is a
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br Efforts to address malnutrition maternal
2019-05-22
Efforts to address malnutrition, maternal and child mortality, and other global health priorities are heavily reliant on behaviour change, including adoption and correct use of health technology, and following treatment recommendations. One long-standing concern is the limited effectiveness of man
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Welcome to volume two of the the first
2019-05-22
Welcome to volume two of the , the first journal devoted to the multidisciplinary management of bone disease in cancer patients. During the past year, the importance of bone oncology in cancer care has continued to increase. This follows the emergence of further clinical data supporting the use of b
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br Discussion PLSVC can be encountered for the first
2019-05-22
Discussion PLSVC can be encountered for the first time during electrophysiological procedures. It is the most common variation in the thoracic venous system and is estimated to be present in 0.3–0.5% of the general population and in 5–10% of patients with other congenital heart defects [3]. It ca
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The appearance of J wave or ER
2019-05-22
The appearance of J wave or ER is now recognized to predispose to the development of arrhythmogenesis when associated with other cardiac disorders, such as ischemia, RO4929097 manufacturer failure, and hypothermia. The J wave might predict prognosis of cardiac events in various heart diseases, and
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