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The concept of metronomic chemotherapy began in
2019-06-14
The concept of metronomic chemotherapy began in the 1990s, when Kerbel showed chemotherapeutic agents may be able to target tumor vessel endothelial cells. In 2000, Browder et al demonstrated a more frequent, lower dose of cyclophosphamide, i.e. anti-angiogenic schedule, could induce response in tum
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Moving forward we identify several urgent needs and challeng
2019-06-14
Moving forward, we identify several urgent needs and challenges. First, the standing of alcohol dehydrogenase inhibitor health workers in the health-care systems needs to be legitimised and moved away from largely grant-funded temporary employees or volunteers who might provide educational services
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Por su parte Juan Carlos Grijalva titula su
2019-06-14
Por su parte, Juan Carlos Grijalva titula su artículo “A caballo, por la ruta de los libertadores: el legado mesiánico y elitista de José Vasconcelos en Ecuador”. Grijalva explica que el ensayista mexicano llegó XL184 cost Ecuador el 17 de junio de 1930 procedente de Colombia, cabalgando los Andes a
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br Case report We report
2019-06-14
Case report We report a case of an 18 year-old Caucasian male who was found to have thrombocytopenia at birth, with a platelet count of 58,000/mm3. Bone marrow biopsy was first performed in 1993, at 13 months of age, and showed 70–80% cellular marrow with occasional megakaryocytes and no evidence
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GSK461364 br Eva Leticia Ordu a Trujillo investigadora
2019-06-13
Eva Leticia Orduña Trujillo, investigadora del en uno de sus más recientes libros , aborda un tema fundamental para explorar, debatir y profundizar sobre nuestras aún muy débiles democracias latinoamericanas, GSK461364 través de la actuación de nuestros estados en sedes judiciales internacionales.
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Another mechanism is that J waves represent a repolarization
2019-06-13
Another mechanism is that J waves represent a repolarization abnormality where J waves are created by the transmural voltage gradient [16]. During myocardial ischemia, the membrane ionic currents are known to be augmented, in turn augmenting the transient outward current (Ito). Augmented Ito would r
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Calcitriol The Cochrane review on exercise after lung resect
2019-06-13
The Cochrane review on exercise after lung resection identified three randomized trials involving 178 participants. The meta-analysis found that exercise capacity was statistically greater in the exercise training group compared to the control group following lung resection for NSCLC. No between-gro
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br Materials and methods br Results br
2019-06-13
Materials and methods Results Discussion The present study has demonstrated that the Wavelet discrimination algorithm is affected by myopotential interference, as evidenced by the large number of patients (55%) showing positive morphology change (defined as the percent-match score of the Wa
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br Materials and methods br Results
2019-06-13
Materials and methods Results Discussion Conclusions Conflict of interest Acknowledgments Introduction Circumferential hiv integrase (PV) isolation has been accepted by a consensus as the strategy for the treatment of atrial fibrillation (AF) using catheter ablation [1–4]. Howe
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br Perioperative risk assessment of thromboembolism
2019-06-12
Perioperative risk assessment of thromboembolism The current thromboembolic risk stratification is largely based on indirect evidence from studies outside of the perioperative setting involving patients with a mechanical order THZ2 valve, chronic atrial fibrillation or venous thromboembolism who
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DALYs as a tool for measuring the
2019-06-12
DALYs, as a tool for measuring the burden of breast cancer, is useful for public health and for burden of disease analyses. DALYs can add useful available information for monitoring services and conducting health-related economic analyses for cost-effective planning in the country. As noted earlier,
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years ago published a groundbreaking and taboo breaking Seri
2019-06-12
5 years ago, published a groundbreaking (and taboo-breaking) Series on stillbirths. Its powerful mix of advocacy and hard data attracted more media attention than perhaps any other Series, and made waves on numerous levels, from the individual to the intergovernmental. Working closely with countrie
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It was imperative to make
2019-06-12
It was imperative to make patients a first priority who had a definitive diagnosis needing immediate, timely, and effective interventions, including primary coronary intervention (PCI), permanent Calcitriol manufacturer implantation, and were most likely to be admitted to CCU postprocedurally (Table
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br Heart rate turbulence HRT HRT was
2019-06-12
Heart rate turbulence (HRT) HRT was introduced by Schidmt in 1999 [11]. It refers to the physiological phenomenon in response to a premature beat. After a ventricular premature contraction (VPC) and a compensatory pause, there is an increase in blood pressure because of the prolonged filling. Ref
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br Conflict of interest br Introduction Far field sensing
2019-06-12
Conflict of interest Introduction Far-field sensing of the atrial electrogram by a ventricular inhibited (VVI) pacemaker is a rare but potentially catastrophic phenomenon if there is no escape rhythm [1–3]. In this setting, the tip of the pacemaker lead is usually located in close proximity to
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