• Similarly to other investigations the

  2019-07-13

  

  Similarly to other investigations, the present study found that ZEA in high concentrations decreases viability of both normal (Liu et al., 2018, Zheng et al., 2018a, Zheng et al., 2018b) and cancer Ibandronate sodium (Khosrokhavar et al., 2009, Kowalska et al., 2017). The toxic effect of ZEA observ

• EphB promotes tumor growth by stimulating

  2019-07-13

  

  EphB4 promotes tumor growth by stimulating angiogenesis through EphrinB2 [18]. However, the distinct and specifically involvement of Altiratinib and veins in the tumor angiogenesis of all tumor grades is unclear. Our results indicate that the relation between EphrinB2 and EphB4 stained blood vessel

• Epac proteins consist of a carboxyl

  2019-07-13

  

  Epac proteins consist of a carboxyl-terminal catalytic region and an amino-terminal regulatory region, which harbors one cAMP-binding domain in Epac1 and two in Epac2 [22], [32], [51]. In the absence of cAMP, the regulatory region covers the CDC25-homology domain and autoinhibits Epac\'s enzymatic a

• br Materials and methods br Results

  2019-07-13

  

  Materials and methods Results and discussion Concluding remarks Together, the results of the theoretical kinetic simulations and of the analysis of the experimentally determined kinetic data of SoBADH performed in this work show that ignoring substrate inhibition causes potentially importan

• the most successful film Over the past decade targeting DNA

  2019-07-12

  

  Over the past decade, targeting DNA repair proteins has emerged as an effective tool to enhance chemosensitivity of malignant cells [9]. However, identification and selection of the proper target of DNA repair pathways is critical to increase cytotoxic activity of chemotherapeutic agents in cancer c

• br Conflicts of interest br Introduction Diacylglycerols DAG

  2019-07-12

  

  Conflicts of interest Introduction Diacylglycerols (DAGs) and phosphatidic Canine ANGPTL7 / Angiopoietin-like 7 Protein (Fc Tag) (PA) play fundamental roles in biology as basic components of membranes, intermediates in lipid metabolism, and secondary messengers in cellular signaling (Carrasco

• cathepsin inhibitor The different diagnostic outcomes of the

  2019-07-12

  

  The different diagnostic outcomes of the two assays are also dependent on the used stimuli. The QuantiFERON-CMV assay targets CD8 + T cathepsin inhibitor by using peptides whereas the T-Track-CMV targets CD4+ and CD8 + T cells by stimulation with two viral proteins [18]. In our study, a specificit

• br Acknowledgment br Introduction Pesticides are largely use

  2019-07-12

  

  Acknowledgment Introduction Pesticides are largely used in agriculture to enhance food production and, to a lesser extent, to control unwanted pests and disease vectors in public health. However, these compounds are often associated with toxicity in non-target species including humans. Occupat

• So far few studies have been

  2019-07-12

  

  So far few studies have been conducted on the role of chemokines in patients with PTSD and avoidant personality disorders. Ogłodek et al. [10] in her studies found an increase in the level of the chemokine CCL-5 in patients with avoidant personality disorder and general anxiety disorder (GAD) as com

• Although many neurotransmitters e g catecholamines serotonin

  2019-07-12

  

  Although many neurotransmitters (e.g., catecholamines, serotonin, and excitatory/inhibitory amino acids) have been implicated in the modulation of anxiety-like responses (Carobrez et al., 2001, Molchanov and Guimaraes, 2002, Vianna et al., 2001), the so-called atypical neurotransmitters, endocannabi

• Epinephrine HCl weight br Author contribution br Acknowledge

  2019-07-12

  

  Author contribution Acknowledgements QNRF grant number NPRP6-065-3-012, Qatar National Research Fund, Doha Qatar for funding this work with grant number NPRP No.: NPRP6-065-3-012. Introduction Preeclampsia (PE) affects 3–5 % of pregnancies worldwide and is one of the leading causes of mate

• Finally the effect of the BMIM BF concentration change on

  2019-07-12

  

  Finally, the effect of the [BMIM][BF4] concentration change on the P-T diagram of methane hydrate was predicted using the proposed model. Three various concentrations (including 10%, 15% and 20%) were considered for calculations. The experimental data [49] and modeling results are demonstrated and c

• Application of the CPH model relies on

  2019-07-12

  

  Application of the CPH model relies on the assumption that the hazard ratio of two observations is constant over time [2]. This enables us to infer the rate of risk of the treatment. For example, in the study of patients with pulmonary arterial hypertension (PAH) [5], the hazard ratio of a group of

• Ligand independent activation of neuronal nuclear

  2019-07-12

  

  Ligand-independent activation of neuronal nuclear estrogen receptors may also continue to occur in absence of ovarian estrogens. AF-1 requires intracellular kinase cascade-dependent phosphorylation of specific residues in the A/B domain of nuclear estrogen receptors (Le Goff et al., 1994; Kato et al

• The defining molecular feature of Ewing sarcoma

  2019-07-12

  

  The defining molecular feature of Ewing sarcoma is the characteristic EWSR1/ETS fusion protein, most commonly involving EWSR1 and FLI1 (Delattre et al., 1992, May et al., 1993). EWS–FLI1 causes global changes in gene expression both by directly regulating gene expression and by causing changes in ch

16019 records 1025/1068 page Previous Next First page 上5页 10211022102310241025 下5页 Last page